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#drugoftheday Diltiazem (Cardizem)-drug class: calcium channel blocker (CCB) Diltiazem (Cardizem) is a Class IV antiarrhythmic and one of the most common pharmacological agents used for treatment of AFib w/RVR (rapid ventricular response). Class IV antiarrhythmics are Calcium Channel Blockers (CCBs), which inhibit intracellular calcium influx via calcium channel antagonism.🖤💙 Although dosages may vary based on physician orders, protocols and age, a standard initial dose is 0.25 mg/kg, ranging between 10-20 mg over 2 minutes, with a second dose of 0.35 mg/kg, ranging between 20-25 mg over 2 minutes, often followed by a 5-10 mg/hr infusion. 💉 Typically, patients are given a bolus, followed by a gtt (drip). Treatment of hemodynamically unstable patients in narrow QRS complex AFib w/RVR requires synchronized cardioversion at 120-200 J initially, and should not be delayed for administration of an anti-arrhythmic agent.
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