Sepsis Alert💉🦠Vanco

• @theedtraumacist Vancomycin is a tricyclic glycopeptide antibiotic used to cover gram➕bacteria such as methicillin resistant Staphylococcus aureus. 💉

Vancomycin works by inhibiting bacterial cell wall synthesis by binding to D-alanyl-D-alanine cell wall precursors, inhibiting polymerization and preventing linkage to the glycopeptide polymer located within the bacteria’s cell wall.

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When dosing vancomycin a couple of factors should be considered including the patient’s weight, renal function, and presenting disease state. It is normally

dosed at 15-20 mg/kg, and even higher for more severe infections (25-30 mg/kg in patients with sepsis, infective endocarditis, meningitis, etc. with a max dose depending on your hospital protocol).

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In a study by Fuller and colleagues that reviewed vancomycin management in the ED, they reviewed 4441 doses of vancomycin given to patients with a weight measurement available. Vancomycin was dosed correctly in only 22.1% of patients 😧 with 71 % of patients being dosed below the recommended dose of 15-20 mg/kg 😱. Vancomycin dosing is not one size fits all and patient specific characteristics should be considered when dosing this medication. 💉

#theedtraumacist #trauma #traumaninjas #miamitrauma #traumiami #emergencymedicine #emergencydepartment #pharmacy #pharmacylife #pharmlife #pharmvida #pharmsohard #pharmacystudent #pharmacyresident #pharmer

About the Author
I am an experienced trauma nurse who has seen a lot of super tragic and gnarly things. On the flip side, I’ve have seen and done a lot of amazing things in my 20 years of nursing as well. I’ve saved lives for a living and I have had the privilege and the honor of holding patients hands as they take their last breath. I have seen SO many patients and their loved ones in their most fragile moments. I am proud of my profession, and for the fact that I have fought so valiantly to be here. Sometimes nurses get burnt out, but I have been blessed to be at the bedside all of my career. I have earned multiple degrees and certifications in nursing. I am the nurse you want at your bedside when you’re critically injured and dying. I put my blood, sweat and tears into being clinically astute & relevant. This blog is to help new nurses, nursing students, paramedics, experienced nurses, or whomever comes across my blogs path and think it is intriguing, educational or inspiring to them. In this career, we are all here to share and help one another grow. I believe in building others up, so they can reach the next level, whatever their goal may be. Carpe Diem & ENJOY!

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